Visual and Auditory Evoked Potentials in Multiple Sclerosis, Parkinson’s Disease and Brainstem Vascular Lesions
DOI:
https://doi.org/10.5644/Radovi.383Keywords:
Multiple sclerosis, Parkinson's disease, Brainstem vascular lesions, Visual evoked potentials, Auditory evoked potentialsAbstract
The aim of this study was analysis of abnormality of visual (VEP) and auditory evoked potentials (AEP) in patients with multiple sclerosis, Parkinson's disease (PD) and brainstem vascular lesions (BSVL). The study included 29 patients with MS (10 males or 34.5%, 19 females or 65.5%) with the mean age of 39.2+/-10.6 years; 59 PD patients (33 or 55.9% males and 22 or 44.1 % females) with average age of 63.79+/-7.97 years, and 40 patients with BSVL (22 males or 55.0%, 18 females or 45%) with mean age of 53.5+/-12.0 years. Evoked potentials were done using “Premier” machine (“Medelec” company) and disc electrodes placed over the scalp according to international 10-20 electrodes placement. Visual stimulus “pattern reversal” for VEPs and auditory stimulus “click” type for AEPs was chosen. All analyses were performed in Division of Clinical Neurophysiology (Lab for EPs), Department of Neurology, University of Tuzla, and obtained parameters were compared with laboratory standards. In MS patients VEP abnormalities were found in 27 (93.1%), and AEP in 24 (82.8%) of them; the VEP abnormalities in PD patients were found in 29 (49%), and AEP in 32 out of 41 (78.1%) cases; in the BSVL patients AEP abnormalities were found in 37 (92.5%) cases. It is concluded that different abnormalities of visual and auditory evoked potentials in multiple sclerosis, Parkinson's disease and brainstem vascular lesions are common findings in routine clinical neurophysiology testing, and very important for diagnostics and evaluation of these disorders.
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