Clinical and therapeutic data of a child with ecthyma gangrenosum

Ilirjana Bakalli, Sashenka Sallabanda, Elmira Kola, Robert Lluka, Ferit Zavalani, Raida Petrela, Ermela Gjyzeli


The presence of the Pseudomonas aeruginosa infection inhealthy children is very uncommon. Infants may occasionallypresent with community-acquired sepsis due to Pseudomonasaeruginosa, preceded by prolonged contact withcontaminated bath water. Ecthyma gangrenosum is a characteristicdermatological manifestation caused most commonlyby Pseudomonas aeruginosa. We describe the clinical dataand therapeutic management of a 6 month-old infant withecthyma gangrenousum caused by Pseudomonas aeruginosa,complicated with septicaemia and meningitis. The infant wasimmunodeficient as indicated by hypogammaglobulinemia,neutropenia, and a low level of C3 complement component.


Pseudomonas aeruginosa; Ecthyma gangrenosum; Immunodeficiency; Neutropeni; Infant

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Basil J, Holly Z, Davis W. Atlas of pediatric physical

diagnosis-third edition. St. Louis: Mosby-Wolfe. 1997;364-5.

Boisseau AM, Sarlangue J, Perel Y, Hehunstre JP, Taïeb A, Maleville J . Perineal ecthyma gangrenosum in infancy and early childhood: septicemic and nonsepticemic forms. J Amer Acad Derm. 1992;27:415-8.

Brady MT, FeiginRD. Pseudomonas and related species. In: Feigin RD, Cherry J D, ed Textbook of pediatric infectious diseases. 4. ed. Philadelphia: W.B.Saunders. 1998;1401-13.

Dunkle LM, Abramowsky C. An 11-month-old infant with fatal Pseudomonas aeruginosa septicemia. Pediatr Infect Dis J. 1991;10(10):772-7.

Fergie JE, Patrick CC, Lott L. Pseudomonas aeruginosa cellulitis and ecthyma gangrenosum in immunocompromised

children. Pediatr Infect Dis J. 1991;10(7):496-500.

Greene SL, Su WP, Muller SA. Ecthyma gangrenosum: report of clinical, histopathologic, and bacteriologic aspects of eight cases. J Am Acad Dermatol. 1984;11(5 Pt 1):781-7.

Huminer D, Siegman-Igra Y, Morduchowicz G, Pitlik SD. Ecthyma gangrenosum ithout bacteremia. Report of six cases and review of the literature. Arch Intern Med. 1987;147(2):299-301.

Ng W, Tan CL, Yeow V, Yeo M, Teo SH. Ecthyma gangrenosum in a patient with hypogammaglobulinemia. J Infect. 1998;36(3):331-5.

Reymond D, Frey B, Birrer P. [Invasive Pseudomonas aeruginosa and Ecthyma gangrenosum infection in a child without risk factors]. Arch Pediatr. 1996;3(6):569-72.

Richard E. Behrman; Robert M. Kliegman; Hal B. Jenson.-Nelson textbook of pediatrics-17th ed.; 2004. p. 725-2226.

Sevinsky LD, Viecens C, Ballesteros DO, Stengel F. Ecthyma gangrenosum: a cutaneous manifestation of Pseudomonas aeruginosa sepsis. J Am Acad Dermatol. 1993;29(1):104-6.

Wong SN, Tam AY, Yung RW, Kwan EY, Tsoi NN. Pseudomonas septicaemia in apparently healthy children. Acta Paediatr Scand. 1991;80(5):515-20.

De Vos FY, Middelburg TA, Seynaeve C, de Jonge MJ. Ecthyma gangrenosum caused by Pseudomonas aeruginosa in a patient with astrocytoma treated with chemotherapy. J Infect Chemother. 2010;16:59–61.

Yassaee M, Berger Elmariah S, Perelman RO, Ubriani R, James WD, Gross PR. Ecthyma Gangrenosum. eMedicine-Dermatology, 2008. Available from:


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