Utility and Algorithm of Imaging Modalities in Diagnosis and Staging of Bronchogenic Carcinoma
DOI:
https://doi.org/10.5644/6Keywords:
bronchogcnic carcinoma, diagnosis, algorithm, imaging modalitiesAbstract
The utility and algorithm of diagnostic and particularly radiological conventional and digital methods in diagnosis and staging of central and peripheral, non-small cell and small cell bronchogenic carcinoma are presented in this paper.
Their sensitivity and specificity in the assessment of malignant mediastinal and hilar adenopathy, pleural and chest wall infiltration and tissue categorization of the solitary
pulmonary nodule are discussed.
It is concluded that digital methods - spiral CT, US and MRI, in spite of quoted limitations, have considerably improved the diagnosis and staging of bronchogenic carcinoma.
Although CT is superior over conventional radiological methods, it should be used in definitive staging complimentary with the other imaging modalities, endoscopic and bioptic methods, as well as obligatory histological confirmation of the diagnosis.
References
Bunn PAJr. Lung cancer: current understanding biology, diagnosis, staging and treatment. Bristol-Myers Company, 1988.
Mackay J, Eriksen M. The Tobacco Atlas. World Health Organization, 2002.
Nielsen ME, Hcaston DK, Dunnick NR, Korobkin M. Preoperative CT evaluation of adrenal glands in non-small cell bronchogenic carcinoma. AJR 1982; 139:317-20.
Gralla RJ. Preoperative and adjuvant chemotherapy in non-small cell lung cancer. Semin Oncol 1988; 15:8.
Armstrong JG, Martini N, Kris MG. Induction chemotherapy for non-small cell lung cancer with clinically evident mediastinal lymph node metastases: the role of postoperative radiotherapy. Int J Radiat Oncol Biol Phys 1992; 23: 605.
Yashar J, Weitberg AB, Glicksman AS. Preoperative chemotherapy and radiation therapy for stage III a carcinoma of the lung. Radiology 1993; 186:586.
Potepan P, Meroni E, Spagnoli I, et al. Non-small cell lung cancer: detection of mediastinal lymph node metastases by endoscopic ultrasound and CT. Eur Radiol 1996; 6: 19-24.
Pugatch RD. Radiologic evaluation in chest malignancies. A review of imaging modalities. Chest 1995; 107 (6 Suppl): 294 S-297 S.
Ihde DC, Hansen HH. Staging procedures and prognostic factors in small cell carcinoma of the lung. In Grcco FA, Oldham RK, Bunn PAJr (eds): Small cell lung cancer. New York, Grune and Stratton, 1981: 261-83.
Faling LJ, Pugatch RD, Jung-Legg Y, et al. Computed tomographic scanning of the mediastinum in the staging of bronchogenic carcinoma. Am Rev Respir Dis 1981: 124-690.
Pugatch RD. Bronchogenic carcinoma. In Mc Neil BJ, Abrams HL (cds): Brigham and womcn's hospital handbook of diagnostic imaging. Little, Brown and Company, Boston-Toronto, 1986: 254-8.
Levvis JWJr, Pearlberg JL, Beute GH, et al. Can computed tomography of the chest stage lung cancer? Yes and no. Ann Thorac Surg 1990; 49: 591-596.
Primack SJ, Lee KS, Logan PM, et al. Bronchogenic carcinoma: utility of CT on the evaluation of patients with suspected lesions. Radiology 1994; 193: 795-800.
Hanson JA, Armstrong P. Staging intrathoracic non-small-cell lung cancer. Eur Radiol 1997; 7: 161-172.
Daly BDTJr, Faling LJ, Pugatch RD, et al. Computed tomography: An effective technique for mediastinal staging in lung cancer. J Thorac Cardiovasc Surg 1984; 88:486.
Daly BDTJr, Faling LJ, Gunars Bite PAC, et al. Mediastinal lymph node evaluation by computed tomography in lung cancer: an analysis of 345 patients grouped by TNM staging, tumor size and tumor location. J Thorac Cardiovasc Surg 1987; 94: 664-672.
Webb WR, Gatsonis C, Zerhouni EA, et al. CT and MR imaging in staging non-small cell bronhogenic carcinoma. Radiology 1991; 178: 705-713.
Mc Loud TC, Bourgonin PM, Greenberg RW, et al. Bronchogenic carcinoma: analysis of staging in the mediastinum with CT by correlative lymph node mapping and sampling. Radiology 1992; 182: 318.
Glazer GM, Orringer MB, Gross BH, et al. The mediastinum in non-small cell lung cancer: CT - surgical correlation. AJR 1984; 142: 1101.
Shin MS, Anderson SD, Myers J, Ho KJ. Pitfalls in CT evaluation of chest wall invasion by lung cancer. J Comput Assist Tomogr 1986; 10 (1): 136-8.
Haggar AM, Pearlberg JL, Froelich JW, et al. Chest wall invasion by carcinoma of the lung: Detection by MRI. AJR 1987; 148: 1075-8.
Mc Loud TC, Filion RB, Edelman RR, Shepard JA. MR imaging of superior sulcus carcinoma. J Comput Assist Tomogr 1989; 13: 233-239.
Mountain CT, Libshitz HJ and Hermes KE. Lung cancer. A Handbook for Staging, Imaging and Lymph Node Classification. Charles P. Young Company, Houston, Texas, USA, 1999.
Godvin JD, Speckman JM, Fram EK, et al. Distinguishing benign from malignantpulmonary nodules by CT. Radiology 1982; 144: 349.
Pugatch RD. Solitary pulmonary nodule. In Mc Neil BJ, Abrams HL (cds): Little, Brown and Company, Boston-Toronto, 1986; 129-33.
Siegelman SS, Zerhouni EA, Leo FP, ct al. CT of the solitary pulmonary nodule. AJR 1980; 135: 1.
Gurney JW. Missed lung cancer at CT: imaging findings in nine patients. Radiology 1996; 199 (1): 117-122.
Tarver RD, Holden RW, Ellis JH. Experimental lung nodule model: CT numbers, nodule size, and actual calcium content. J Comput Assist Tomogr 1983; 7(3): 402-6.
Seltzer SE, Judy PF, Adams DF, et al. Spiral CT of the chest: comparison of cine and film-based viewing. Radiology 1995; 197 (1): 73-78.
Kaneko M, Eguchi K, Ohmatsu H, et al. Peripheral lung cancer: screening and detection with low-dose spiral CT versus radiography. Radiology 1996; 201 (3): 798-802.
Mori K, Tominaga K, Hirose T, et al. Utility of low-dose helical CT as a second step after plain chest radiography for mass screening for lung cancer. J. Thorac Imaging 1997; 12 (3): 173-180.
Obuchi M, Shen Y, Nagashima J, et al. Examination of scanning technique for lung cancer screening with helical CT. Nipon Igaku Hoshasen Gakkai Zasshi 1997; 57 (1): 12-18.
Diederich S, Wormanns D, Leuzen H, et al. Screening asymptomatic early bronchogenic carcinoma with low dose CT of the chest. Cancer 2000; 89(11 Suppl): 2483-4.
Kickuth R, Kirchner J, Laufer U, et al. Better visualization of transbronchial biopsy using CT fluoroscopy. Cardiovasc Intervent Radiol 2000; 23 (5): 347-50.
Bungay HK, Pal CR, Davies CW, et al. An evaluation of computed tomography as an aid to diagnosis in patients undergoing bronchoscopy for suspected bronchial carcinoma. Clin Radiol 2000; 55 (7): 554-60.
Kanczor HU, Kreitner KF. Contrast enhanced MRI of the lung. Eur J Radiol 2000; 34 (3): 196-207.
Ohno Y, Adachi S, Motoyama A, et al. Multiphase ECG - triggered 3D contrast - enhanced MR - angiography: utility for evaluation of hilar and mediastinal invasion of bronchogenic carcinoma. J Magn Reson Imaging 2001; 13 (2): 215-24.
Rapp - Bernhardt U, Welte T, Doehring W, et al. Diagnostic potential of Virtual bronchoscopy: advantages in comparison with axial CT slices, MPR and MIP? Eur Radiol 2000; 10 (6): 981-8.
Haag DW, Follette DM, Roberts PF, et al. Advantages of positron emission tomography over computed tomography in mediastinal staging of non-small cell lung cancer. J Surg Res 2002; 103 (2): 160-4.
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