Seroepidemiological Study Of Vaccinated Children Against Measles, Rubella And Mumps In Three Districts Of Bosnia And Herzegovina
DOI:
https://doi.org/10.5644/Radovi.244Abstract
147 sera have been tested in hemagglutination inhibition test (measles and rubella) and haemolysis reaction in Gel (mumps).
- From 57 children sera tested for measles, 26 sera (45,61%) were negative before vaccination. Ali sera had titters 1:4 or more, except two sera with a titter 1:2. After one-year all sera were positive at least 1:4.
- From 35 children sera tested for rubella, all sera had higher titters 6 Weeks and one year after vaccination than the titters before vaccination.
- From 25 children sera tested for mumps, 22 or 88% had no H. I. titters before vaccination. 6 weeks and one year after vaccination all sera have positive seroconversion.
- The titters of 58 fourteen-year-old vaccinated girls 6 weeks after vaccination were high at least 1:32.
This work showed that a domestic attenuated triple vaccine against measles, rubella and mumps, (production of “Institute of Immunology” — Zagreb, Yugoslavia) is immunogenic and that it gives high rate of seroconversion.
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