The Dosage of Antipsychotic Drugs in the University Departments of Psychiatry in Federation of Bosnia and Herzegovinia
DOI:
https://doi.org/10.5644/Radovi.398Keywords:
antipsychotics, schizophreniaAbstract
The aim of this pharmaco-epidemiological study was to establish which antipsychotic are currently in use and determine in what daily dosages these drugs are given to patients in three Psychiatric departments in the Federation of Bosnia and Herzegovina (Sarajevo, Tuzla, Mostar).
Majority of patients received classic antipsychotic medications. In Sarajevo most frequently administered was promazine, orally and parenteral, for total of 38 patients or 28, 6% of Sarajevo sample. In Tuzla most frequently, administered antipsychotics were haloperidol and thioridazine for 20 and 21 patients, which are 19, 2%, and 20, 2% of total number of patients in Tuzla. In Mostar the leading antipsychotic is haloperidol, orally administered, and with which 29 patients were treated. This represent 31,2% of total number of patients in Mostar.
Clozapine was applied in all three centres but in very small percentage of cases. Treatment with daily doses antipsychotics in the Department of Psychiatry in University Clinical Centres in Federation of Bosnia and Herzegovina are mainly in accordance with interactional standards. Only problem is area of simultaneous use of multiple antipsychotics, both in acute and chronic cases, and frequent use of antiparkinsonics in chronic cases. Because of disseminated results, were considered that the continuous medical education will lead to improvement of treatment quality for the patients with schizophrenia.
References
Jibson MD, Tandon R. Treatment of schizophrenia. Psychiatry. Clin. North Am. 2000; 7: 83-113.
Katzung BG. Basic and Clinical Pharmacology, Eighth Edition, the McGraw-Hill Companies. 2001; 478-490.
Loga S i Fišekovic S. Psychopharmacoterapy, in: Shizophrenia (S. Loga and S. Fišekovic Ed.) Faculty of Medicine Sarajevo. 2000; 24-117.
Baldessarini RJ, Kando JC, Centorrino F. Hospital use of antipsychotic agents
in 1989 and 1993: stable dosing with decreased length of stay. Am J Psychiatry 1995; 152(7): 1038-44.
Van der Zwaag C., McvGee M., McEvoy, J.P., Freuden-Reich O., Wilson, W.H, Copper TB. Response of patients with treatment - refractory schizophrenia to clozapine within three serum ranges. American Journal of Psychiatry, 1996; 153:1579-84.
Fleischhacker WW. Drug Treatment of Schizophrenia. In: Maj M, Sartorius N (Eds). Schizophrenia. 1999; Chichester: John Wiley & Sons Ltd.
Lieberman JA. Atypical antipsychotic drugs as a first line treatment of schizophrenia: A rationale and hypothesis. Journal of Clinical Psychiatry 1996; 57 (Suppl 11): 68-71
Yip KC. Ungvari GS. Cheung H.K., NG, FS. Lau, S.T. (1997): A survey of antipsychotic treatment for schizophrenia in Hong Kong. Chin MedJ(Engl) 1997; 110(10):792-6.
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