The Changes in Microscopic Structure of the Wall of Coronary Arteries in Relation to Muscular Formations Observed From the Aspect of Growth Anatomy and From the Aspect of Perfusional Theory of Arterosclerosis
DOI:
https://doi.org/10.5644/Radovi.188Abstract
By dissection and microscopic method, using 71 human hearts of persons of both sex, ranging from new-borns to those 81 years of age, we have examined muscular formations on coronary arteries and structure of arterial wall in the area of muscular formation, proximal and distal to it.
Out of the 71 examined subjects, 37 were found to have muscular formations, that is, in 52% of the examined cases. It \vas established that 32 cases had one muscular formation either on the left or the right coronary artery; 4 cases were found with two muscular formations and 1 case having three muscular formations.
In the left type of branching of the coronary arteries, muscular formations were found in 85.7% of the examined cases; 21,696 of the examined cases had muscular formations in the right type of branching of the coronary arteries and 78.9% of the examined cases had muscular formations in the symmetrical branching. Muscular formations on the coronary arteries were found in the new-borns. Fibres of muscular formations are mainly arranged transversely to the direction of the blood vessel. We discovered only five muscular formations with a larger number of oblique and longitudinal fibres, but in those cases transversal fibres prevailed.
By microscopic examinations, a rapid development of the intima and (media of coronary arteries during growth and development of the body was established. From 0,5—20 years of age, intima progressively thickens, but that thickening is always greater proximal to muscular formation. From 21—50 years of age, intima is the thickest proximal to muscular formation. In the older members of this group, lesions of the blood vessel wall can be seen, which are usually mostly manifested proximal to the muscular formation. In the group of 50-year olds and older subjects, arteriosclerotic changes are more developed proximal to the muscular formation.
References
Berg, R., Vber das Auftreten von Myocardbriicken ilber den Koronargefassen beim Schwein (Sus scrofa domesticus). Anatomischer Anzeiaer, Bd. 112, 25—31, 1963.
Biichner, F., Chronische Hypertonie als ein Faktor in der Entstehnng der Arteriosklerose. Buli. Schw. Akad. Med. Vissensch. 13, 127—138, 1957.
Čumakov, A., Reparativnyje processy v aorte posle udaljenija ee adventiciji. Arch. patol. (Moskva) 7, 19—25, 1965.
Doerr, W., Morfologische Untersućhungen zur Entstehnng der Aortensklerose. Dtsch. med. Wschr. 85, 1401—1405, 1417—1421, 1960.
Doerr, W., Perfusionstheorie der Arterisklerose. G. Thieme Ver. Stuttgart, 1963.
Džavahišvili, H. A., Komahidze, M. E., Sosudi serdca. Izdateljstvo Akademii nauk Gruzinskoj SSSR, Tbilisi, 1963.
Edwards, J. E., Burnsides, J. E., Arterioskleroz intra i ekstra muraljnih otrezah venečnih arterij serdca čeloveka. Vapr. patol. serdečno sosudistoj sistemi, 1957.
Fritsch, H., Aortensklerose bei gestorter Perftision. Munch. med. Wschr. 107, 152, 1965.
Geiringer, E., The mural coronary. Amer. Heart. J. 1951.
Gmaz-Nikulin, E., Experimental investigation on perftision of the aortic wall in the rabit. Fol. med. Fac. med. Saraev, 2, 165—187, 1967.
Gmaz-Nikulin, E. i Plamenac, P., Poremećaj perfuzije zida aorte kod tumorske infiltracije njene adventicije. Srpski arhiv 96, 9, 905——913, 1968.
Griss, P., Kirsch, J. und Wegener, K., Funktionelle Strukturen grosser Korperschlagadern und ihre Bedeutung fiir den Altersumbau der Intima. Virch. Arch. 342, 319—328, 1967.
Hieronymi, G. Angiometrische Untersuchungen vendser und arterieller Gefosse verschiedener Lebensalter. Frankf. Z. Pathol. 69, 18—36, 1958.
Hristodulo-Finiti, A. S., Arterii serdca čeloveka v nekatorie periodi ontogeneze, Dis. Doneck, 1959.
Kadar, F., Die topographischen Verhaltnisse zwischen Gefassen und Muskelfasern des Herzens. Anatomischer Anzeiger, Bd. 113, 381—386, 1963.
Klassen, A., Sung, J. and Stadlan, E., Histological changes in cerebral arteries with increasing age. J. Neuropathol. and exper. Neurol. 21, 607—623, 1968.
Kriessmann, A. und Wegener, K., Morphologische Langsschnittstudie der linken Plerzkranzschlagader. Virch. Arch. Abt. A. Path. Anat. 349, 332—344, 1970.
Linzbach, J., Die Bedeutung der Gefdssxvandfaktoren fiir die Entstehung der Arteriosklerose. Verth. Dtsch. Ges. Pathol. 41. Tag. 24—41, 1957.
Lisičin, M. S., Tipi krovosnabženija serdca. Vestn. hir. i pogr. obi., IX, 26—27, 1927.
Meyer, W., Vber die rhytmische Lokalisation der arterosklerotischen Herde im cervicalen Abschnitt der Vertebralarterie. Beitr. path. Anat. 130, 24—39, 1964.
Milch, R., Metrici properties of the aging arterial wall. Monogr. in the Surg. Sciences Vol. 2/4, 261—341, 1965.
Niuller, E. und Friedlein, M., Messergebnisse bei coronarsklerotischem Mediaschvund und Intimaumbau und ilire Bedeutung fiir die vasomotorische Durchblutungsregulung. Frankf. Z. Pathol. 69, str. 268—278, 1958.
Papacharalampous, N., Altersedingte histologische und histochemische Veranderugen der Coronargefdsse. Virch. A. 338, 187—193, 1964.
Polaček, P., The occurrence of myocardial bridges and loops in some mammals. Acta Facultatis Medlcae Universitatis Brunensis, 25—30, 1968.
Polaček, P., Zechmeister, A., The occurrence and significance of myocardial bridges and loops an coronary arteries. Acta Facultatis Medicae Universitatis Brunensis, 1—100, 1968.
Tandler, J., Die Gefdsse des Herzens. Anatomie des Herzens, 219—229, 1913.
Voboril, Zg., Contribution to the angioarchitecture of the cardiac muscle of muscle bridges and loops above the coronary arteries of the human heart. Folia Morphologica, No. 1, Vol. 16, 69—73, 1969.
Wegener, K., Bersch, G., Bersch, W., Kuhler, Cl. nud W. W., Morphometrische Untersuchungen zur Coronarsklerose. Virch. Arch. Abt. A. Path. Anat. 356, 76—88, 1972.
Wolkoff, K., Uber die histologische Struktur der Coronararterien des menschlichen Herzens. Virch. Arch. 241, 42—58, 1923.
Wolkoff, K., Uber die Atherosklerose der Coronararterien des Herzens. Beitr. path. Anat. 82, 555—596, 1929.
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Hajrudin Hadžiselimović, Edita Gmaz-Nikulin, Drenka Šećerov
This work is licensed under a Creative Commons Attribution 4.0 International License.
