Effects of the Toxins on the Isolated Innervated Human Ureter
DOI:
https://doi.org/10.5644/Radovi.303Abstract
Ureteral motility was studied in isolated innervated human ureter preparations after adding various toxins. Ureters were removed during surgery. Contractions were monitored and recorded isometrically after an electric stimulation. Investigated organic solvents were benzene, xylene and trichlorethylene.
Preliminary results indicate that benzene and trichlorethylene decreased the height of the induced contractions in a dose dependent way. Xylene increased the height of the induced contractions without affecting the base line tone.
Such a preparation has not been used in toxicological investigations so far. The results of preliminary investigations with isolated innervated human ureter are presented in this paper. This preparation seems to be useful in further toxicological investigations.
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