Cardiovascular Diseases in the Old Age With a Special Regard to Pharmacotherapy
DOI:
https://doi.org/10.5644/Radovi.267Abstract
With old people it is possible, with adequate application and dosage schedule, to correct functional disorders till the grade of tolerance. Investigations of pharmacokinetic parameters (especially- of cardiac glycoside) gives a possibility of dosing control and prevention of drug side effects.
In activation periods of various cardiovascular diseases. it is necessary to monitor electrolytic acido-base status of ECG, especially in diabetes, nephrosis, pulmonary heart, pulmonary preedema, etc.
Substitution therapy with potassium and sodium and sufficient quantity of liquids in adequate diet, can prevent new side effects of drugs (diuretics, cardial glycosides).
Depo and retard forms of drugs are indicated in chronic States, but there is a need of attention in simultaneous application of other drugs with different half-life drugs.
Side effects of cardiovascular and other drugs can be prevented by a regular dosage and adequate monitoring of changes.
References
Allman, S. F. (1983): Gastrointestional Diseases in the Elderly. Med. Ciin. N. Am., 67. 433—136.
Brkić, I. i sar. (1986): Saopštenje na Simpoziju o kardiovaskularnim oboljenjima. ANUBiH, Sarajevo.
Cape. R. (1984): Biological Accompaniments oj Ageing, In: Clinical Pharmacology and Drug Treatment in the Elderltj. Shurchill Livinstone, Philadelphia, 1—16.
Epstein, M. (1979): Effect oj Ageing on the Kidney. Federation Proceeding, 33, 168.
Feruglio, F. S. (1975): Heart Diseases, In: Practical Geriatrics. S. Karger, Bazel, 120—138.
Greenblatt, D. J. (1979): Reduced Serum Albumln Concentration in the Elderlg: a Raport From the Boston Collaborative Drug Survcillance Program. J. of the Amer. Geriatric Soc.. 27. 20—25.
Graham-Smith, D. G., and Aronson, J. K. (1984): Oxjord Tcxtbook of Clinical Pharmacologg and Drug Theraptj. Oxford Medical Publications, 178—182.
Harris, R. (1970): The Management oj Geriatric Cardiovascular Diseases. Churchill Livingstone. Philadelphia.
Kannel, W. B., and Gordon, I. (1978): Evaluation oj Cardiovascular Risk in the Elderly. The Framingham Study, Bulletion of the New York Academy of Medicine, 54, 573—591.
Kowar. M. G. (1977): Health oj the Elderly and Use oj Health Service. Public Health Reparts. 92. 9—19.
Meserli, F. H., Glade, L. B., Dreslinski, G. R., Dunn, F. G., Resiw, F., McPhee A. A. Froclich. E. D. (1981): Hgpertension in the Elderly: Haemodynamic Fluid Volume and Endocrine Findings. Clin. Sci.. 61, Suppl. 7,
3935—3945.
Novak. L. P. (1972): Ageing, Total Blood Potassium. Fat-free Mass, and Cell-mass in Males and Females Between Ages 18 and 85 years. J. of Gerontol., 27, 348—442.
Niarchos. A. P., Laragh, J. H. (1980)- Hijpertcnsionin in the Eldery, Pato-physiology. Modem Concept of Cardiovascular Diseases. 49, 43—48.
O’Malley. K. (1984): Clinical Pharmacology and Drug Treatment in the Elderlg. Churchill Livingstone, Philadelphia.
O’Callagham, W., O'Brien, E., and O’Malley. K. (1984): Hypertension in the Elderly. Patophysiology and Management. In: Clinical Pharmacology and Drug Treatment in the Elderly, Churchill Livingstone, 122—138.
Piersnn R. N. Lin. D. H. Y., Philip, R. A. (1974): Total Body Potassium in Health: Effect oj Age, Sex, Height and Fat, Amer. J. of Physiol., 206—210.
Prescott, L. F. (1980): Drug Toxicity. In: Recent Advances in Clinical Pharmacology. Ed. Turner P., and Shand D., 189—204.
Petersen, D. M.. and Thomas. C. W. (1979): Acute Drug Reactions among the Elderly. J. Gerontol., 30, 552—556.
Rowe, J. W. (1983): Ageing and Renul Function. Annual Rcviw of Gerontol., 31. 161—166.
Rowe, J. W., Andres. R., Tobin. J. D., Norris. A. H. and Schick. N. W. (1976): The Efject of Age on Creatine Celarance in Man: a Cross-sectional and Lonaitudinal Study. J. of Gastroenterol., 31, 155—160.
Rossman, I. (1977): Anatomic and Body Changes with Ageing. In: Finch C. and Haylick I. (edes.): Handook of the Biologv Ageine. Von Nostrand Reinhold Comp.. New York.
Rose, G. (1980): The Hypertensive Patients. Pitman Medical. London. 14.
Samy, A. H. (1983): Clinical Investigations oj Diseases in the Elderly. Med. Clin. North Am., 67, 333—336.
Scheiner, L. B. and Melmon. K. L. (1977): The Utility Function of Antihypertensive Therapij. Ann. N. Y. Acad. Sci., 8, 114—121.
Seymor, D. G., Heuschke, P. J., Cape, R. D. T. and Campbell, A. J. (1980): Acute Confusional States of Dementia in the Elderly: the Role of Dehydration, Volume Depletion, Physical Illness and Age. Age and Ageing,
9, 137—142.
Schmidcke, I. and Schoop, W. (1975): Notwendige Diagnostic und Therapie arterieller Durchblutungsstorungen in Alter. Zeitschr. Gerontol., 5, 336—343.
Strandel, T. (1976): Cardiac Output in Old Age. In: Caird F. I., Dali L. C., and Kennedy R. D. (eds.), Plenum press, New York and London. 369—396.
Weidmann, P., Mythenaere, D. C„ Maxwell, M., De Lima. J. (1975): Effect of Ageing on Plasma Renin and Aldosteron in Normal Man. Kidney Internat., 8, 138—143.
Zeiller, E. (1972): Transluminale Verschlussrekanalisation mit Angiographie katheter. Herz Kreisl., 4, 138—143.
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Irfan Zulić, Seid Huković

This work is licensed under a Creative Commons Attribution 4.0 International License.


